Peer-reviewed veterinary case report
Malignant nerve sheath tumor with eosinophilic globules in a dog's
By Sugiyama, Akihiko et al.·Published in The Journal of veterinary medical science·2008·Department of Veterinary Laboratory Medicine, Japan·View original on PubMed →
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Original publication title: Primary malignant peripheral nerve sheath tumor with eosinophilic cytoplasmic globules arising from the greater omentum in a dog.
- Species:
- dog
Plain-English summary
A 10-year-old Golden Retriever was found to have a tumor in the greater omentum, which is a part of the abdominal lining. The tumor was identified as a malignant peripheral nerve sheath tumor, a type of cancer that can affect nerves. The dog showed no specific symptoms mentioned, but tumors like this can often lead to weight loss or abdominal discomfort. Unfortunately, the outcome of the treatment is not detailed in the study, but this case is notable as it may be the first of its kind reported in pets.
People also search for: dog tumor in abdomen · Golden Retriever cancer symptoms · malignant peripheral nerve sheath tumor treatment
Abstract
A 10-year-old Golden Retriever dog had a solitary tumor mass arising from the greater omentum. Histologically, the tumor showed varying cellularity and patterns of cellular arrangement. In dense cellular areas, spindle-shaped cells were arranged in interlacing bundles. The sparse cellular area was characterized by loosely arranged fusiform cells. The neoplastic cells frequently contained PAS-positive eosinophilic globules in the cytoplasm, and mitotic figures were frequently observed. The tumor cells were positive to vimentin, S-100 protein, glial fibrillary acidic protein, myelin basic protein, neuron-specific enolase and myoglobin. The present tumor was diagnosed as a malignant peripheral nerve sheath tumor (MPNST) with eosinophilic cytoplasmic globules arising from the greater omentum. To our knowledge, this may be the first case of primary omental MPNST in domestic animals.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/18685251/