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Peer-reviewed veterinary case report

Primary renal cell carcinoma in two horses.

Journal:
Journal of the American Veterinary Medical Association
Year:
1981
Authors:
Haschek, W M et al.

Plain-English summary

In this study, two horses were diagnosed with renal cell carcinoma, which is a type of kidney cancer. One horse had a large buildup of fluid in the abdomen but showed no other signs of urinary problems, while the other horse had blood in its urine. Both horses had noticeable tumors around their kidneys, with one horse's tumor almost taking over the entire left kidney and spreading to other organs, while the other horse's tumor was pressing on the right kidney. The research also noted that renal cell carcinoma is more common in horses and dogs compared to other animals like cattle, cats, or pigs. Unfortunately, the outcome for these horses is not specified in the abstract.

Abstract

Of 2 horses with renal cell carcinoma, 1 had massive ascites but no other signs of urinary tract disease; the other had hematuria. In both horses, the tumors were palpable as large perirenal masses. The tumor mass of horse 1 almost completely replaced the left kidney, and there were tumor implants on the serosa of abdominal organs. The right kidney of horse 2 was compressed peripherally by the tumor, which completely filled the renal pelvis. The prevalence of renal cell carcinoma in horses and dogs necropsied at the New York State College of Veterinary Medicine between 1953 and 1976 was similar, and these 2 species had a higher prevalence than cattle, cats, or swine.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/7341564/