Peer-reviewed veterinary case report
Pomeranian dog with ureter tumor causing kidney swelling
By Rigas, Johanna D et al.·Published in Veterinary clinical pathology·2012·Department of Biomedical Sciences, United States·View original on PubMed →
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Original publication title: Primary ureteral giant cell sarcoma in a Pomeranian.
- Species:
- dog
Plain-English summary
An 8-year-old male neutered Pomeranian was brought to the vet because of kidney swelling and a mass in his abdomen. During surgery, the vet found a tumor in the ureter (the tube connecting the kidney to the bladder) and removed it. Tests showed that the tumor was a rare type of cancer called giant cell sarcoma. This case is significant because it’s the first documented instance of this specific cancer in a dog. The dog underwent surgery, and while the outcome isn't detailed, the removal of the mass is a crucial step in managing this condition.
People also search for: Pomeranian kidney tumor · dog ureteral cancer treatment · giant cell sarcoma in dogs
Abstract
An 8-year-old male neutered Pomeranian dog was presented to the Veterinary Teaching Hospital at Oregon State University for surgical treatment of hydronephrosis of the left kidney and a left cranial abdominal mass. A primary ureteral mass was found during exploratory surgery, and the mass was resected and ureteral anastomosis was performed. Cytologic evaluation of the mass revealed 3 distinct cell populations, including a large number of multinucleated giant cells, a moderate number of thin spindle-shaped cells, and cohesive clusters of transitional epithelial cells. The cytologic diagnosis was giant cell sarcoma. The diagnosis was confirmed by histologic examination, and immunohistochemical staining was performed. The spindle-shaped cells and multinucleated giant cells were both immunoreactive for vimentin and spindle-shaped cells for S-100. Tumor cells did not express wide-spectrum cytokeratin, broad-spectrum muscle actin, smooth muscle actin, sarcomeric actin, desmin, BLA36, Mac 387, synaptophysin, neuron-specific enolase, glial fibrillary acid protein, or von Willebrand factor. These findings are most consistent with an anaplastic sarcoma with giant cells. This is the first case report of a primary ureteral giant cell sarcoma in a dog.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/22260776/