Peer-reviewed veterinary case report
Prostatic artery embolization for dogs with prostate cancer
By Culp, William T N et al.·Published in Journal of the American Veterinary Medical Association·2021·View original on PubMed →
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Original publication title: Procedural description and prospective evaluation of short-term outcome for the use of prostatic artery embolization in dogs with carcinoma of the prostate.
- Species:
- dog
Plain-English summary
Twenty dogs with prostate cancer underwent a procedure called prostatic artery embolization (PAE) to help reduce their symptoms. Before the treatment, many dogs showed signs like straining to urinate, difficulty passing urine, and lethargy. After the procedure, these symptoms significantly decreased, and all dogs had a noticeable reduction in prostate size. The results were encouraging, suggesting that PAE can help improve the quality of life for dogs suffering from prostate cancer.
People also search for: dog prostate cancer treatment · prostatic artery embolization for dogs · dog straining to urinate · prostate cancer symptoms in dogs
Abstract
OBJECTIVE: To describe the procedure of prostatic artery embolization (PAE) in dogs with prostatic carcinoma and to evaluate the short-term outcome for treated dogs. ANIMALS: 20 client-owned dogs with prostatic carcinomas between May 2014 and July 2017. PROCEDURES: In this prospective cohort study, dogs with carcinoma of the prostate underwent PAE with fluoroscopic guidance. Before and after PAE, dogs underwent CT and ultrasonographic examinations of the prostate, and each owner completed a questionnaire about the dog's clinical signs. Results for before versus after PAE were compared. RESULTS: Prostatic artery embolization was successfully performed in all 20 dogs. Tenesmus, stranguria, and lethargy were significantly less common 30 days after PAE (n = 2, 1, and 0 dogs, respectively), compared with before PAE (9, 10, and 6 dogs, respectively). Median prostatic volume was significantly less 30 days after PAE (14.8 cm3; range, 0.4 to 48.1 cm3; interquartile [25th to 75th percentile] range, 6.7 to 19.5 cm3), compared with before PAE (21.7 cm3; range, 2.9 to 77.7 cm3; interquartile range, 11.0 to 35.1 cm3). All dogs had a reduction in prostatic volume after PAE, with a median prostatic volume loss of 39.4% (95% CI, 20.3% to 59.3%). CONCLUSIONS AND CLINICAL RELEVANCE: Prostatic artery embolization was associated with decreased prostate volume and improved clinical signs in this cohort. The short-term response to PAE appears promising, and evaluation of the long-term impact on survival time is needed.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/34727073/