Peer-reviewed veterinary case report
Survival after lung cancer surgery in small-breed dogs
By Ichimata, Masanao et al.·Published in Journal of veterinary internal medicine·2023·Japan Small Animal Cancer Center, Japan·View original on PubMed →
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Original publication title: Prognosis of primary pulmonary adenocarcinoma after surgical resection in small-breed dogs: 52 cases (2005-2021).
- Species:
- dog
Plain-English summary
A study looked at 52 small-breed dogs diagnosed with lung cancer (pulmonary adenocarcinoma) that had surgery to remove the tumors. The researchers found that the size of the tumor was an important factor in predicting how long the dogs would live after surgery. Dogs with smaller tumors (less than 5 cm) generally had better outcomes, with an average survival time of about 716 days after surgery. The findings suggest that knowing the tumor size can help veterinarians give a better prognosis for small-breed dogs with this type of cancer.
People also search for: small dog lung cancer prognosis · pulmonary adenocarcinoma treatment in dogs · what to expect after dog lung surgery
Abstract
BACKGROUND: Tumor size is an important prognostic factor in lung cancer in dogs, and the canine lung carcinoma stage classification (CLCSC) recently has been proposed to subdivide tumor sizes. It is unclear if the same classification scheme can be used for small-breed dogs. OBJECTIVES: To investigate whether the tumor size classification of CLCS is prognostic for survival and progression outcomes in small-breed dogs with surgically resected pulmonary adenocarcinomas (PACs). ANIMALS: Fifty-two client-owned small-breed dogs with PAC. METHODS: Single-center retrospective cohort study conducted between 2005 and 2021. Medical records of dogs weighing <15 kg with surgically resected lung masses histologically diagnosed as PAC were examined. RESULTS: The numbers of dogs with tumor size ≤3 cm, >3 cm to ≤5 cm, >5 cm to ≤7 cm, or >7 cm were 15, 18, 14, and 5, respectively. The median progression-free interval (PFI) and overall survival time (OST) were 754 and 716 days, respectively. In univariable analysis, clinical signs, lymph node metastasis, margin, and histologic grade were associated with PFI, and age, clinical signs, margin, and lymph node metastasis were associated with OST. Tumor size classification of CLCS was associated with PFI in all categories, and tumor size >7 cm was associated with OST. In multivariable analysis, tumor size >5 cm to ≤7 cm and margin were associated with PFI, and age was associated with OST. CONCLUSIONS AND CLINICAL IMPORTANCE: The tumor size classification of CLCS would be an important prognostic factor in small-breed dogs with surgically resected PACs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/37226683/