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Peer-reviewed veterinary case report

Survival factors in dogs with lymphocytic-plasmacytic enteritis

By Ohno, Koichi et al.·Published in The Journal of veterinary medical science·2006·Department of Veterinary Internal Medicine Graduate School of Agricultural and Life Sciences, Japan·View original on PubMed

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Original publication title: Prognostic factors associated with survival in dogs with lymphocytic-plasmacytic enteritis.

Species:
dog

Plain-English summary

A group of dogs diagnosed with lymphocytic-plasmacytic enteritis (a type of intestinal inflammation) was studied to understand which factors might affect their survival. Among the 48 dogs, those that showed signs of severe weight loss and loss of appetite (anorexia) were less likely to survive beyond six months. The Shiba breed was notably more common among the dogs that did not survive. The study found that dogs with low protein levels in their blood and those who did not respond well to initial treatment had a poorer prognosis. Identifying these signs early can help pet owners and vets make better decisions about treatment options.

People also search for: dog weight loss and loss of appetite · lymphocytic-plasmacytic enteritis in dogs · Shiba Inu health issues

Abstract

Prognostic factors associated with survival in dogs with lymphocytic-plasmacytic enteritis (LPE) were investigated through a retrospective study. Using case records, 48 dogs diagnosed with LPE were classified as survivors (n = 32) or non-survivors (n = 16), and the clinical and clinicopathological parameters were reviewed between the 2 groups by using univariate and multivariate prognostic analysis. Compared to the hospital population, non-survivors had an overrepresentation of the Shiba breed. Results of univariate analysis indicated that anorexia, severe weight loss, packed cell volume, and total protein were significantly associated with survival for 6 months after diagnosis. In multivariate analysis, anorexia and hypoproteinemia were significantly associated with survival. Furthermore, initial response to treatment was strongly associated with poor prognosis. Based on these clinical and laboratory parameters such as anorexia, hypoproteinemia and initial response to treatment, it may be possible to predict poor prognosis in canine LPE.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17019061/