Peer-reviewed veterinary case report
MRI signs in dogs with nasal tumors treated by radiotherapy and their
By Agthe, P et al.·Published in The Journal of small animal practice·2009·Queen's Veterinary School Hospital, United Kingdom·View original on PubMed →
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Original publication title: Prognostic significance of specific magnetic resonance imaging features in canine nasal tumours treated by radiotherapy.
- Species:
- dog
Plain-English summary
A group of 41 dogs with nasal tumors underwent radiotherapy, and researchers looked at specific MRI features to see if they affected survival. They found that having certain MRI signs, like tumor extension into the back of the nasal cavity, didn't significantly impact survival rates or the development of neurological problems in these dogs. While there was a slight trend suggesting shorter survival for dogs with more extensive tumors, the differences weren't strong enough to draw firm conclusions. Overall, the study suggests that dogs without neurological signs at diagnosis may not have a worse outcome, even if their tumors are more advanced.
People also search for: dog nasal tumor treatment · canine radiotherapy prognosis · MRI findings in dog tumors
Abstract
OBJECTIVES: To investigate the prognostic significance of the magnetic resonance (MR) findings of meningeal hyperintensity of the olfactory bulbs and tumour extension into the caudal nasal recess (CNR) in dogs with nasal tumours treated by radiotherapy. METHODS: MR images of 41 dogs with nasal tumours treated with radiotherapy were reviewed. The occurrence of neurological signs and survival of patients with and without meningeal hyperintensity of the olfactory bulbs and tumour extension into the CNR were analysed together with possible confounding factors including intracranial extension and patient age. RESULTS: There was no significant association between the presence of meningeal hyperintensity or CNR involvement and the occurrence of neurological signs. Although there was a tendency towards shorter survival in dogs with tumour extension into the CNR, multivariable analysis showed no significant difference in survival between dogs with/without CNR involvement, meningeal hyperintensity or intracranial tumour extension (P=0.12, 0.50 and 0.57, respectively). CLINICAL SIGNIFICANCE: In dogs with nasal tumours treated with radiotherapy, tumour extension into the cranium is not necessarily associated with shorter survival in patients without neurological signs at time of diagnosis. Although a definite influence of CNR involvement on case outcome could not be demonstrated, studies with a larger population are warranted.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/19954440/