Peer-reviewed veterinary case report
Nasal philtrum artery disease in two Brazilian Mastiff dogs
By Ferreira, Ana Paula C. & Grandi, Fabrizio·Published in Brazilian Journal of Veterinary Pathology·2017·View original on Crossref →
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Original publication title: Proliferative arteriopathy of the nasal philtrum in two Brazilian Mastiff dogs
- Species:
- dog
Plain-English summary
Two Brazilian Mastiff dogs were brought in with unusual growths on their noses. The first dog was treated with oral prednisolone and a topical medication called tacrolimus, while the second dog received pentoxifylline and tacrolimus. After 15 days, the first dog showed no improvement, but the second dog had a mild improvement. These treatments may work well for mild cases, but results can vary.
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Abstract
Proliferative arteritis of the canine nasal philtrum is an unusual disease with an unknown etiology and very few cases described in literature to date. Two patients with characteristic lesions underwent biopsy and confirmation by histopathological assessment. The first case was treated with oral prednisolone once daily and topical tacrolimus twice daily. The second case was treated twice daily with pentoxifylline and topical tacrolimus. Both treatments were successfully used by other authors previously. In result, clinical improvement varied among patients. The lesion of the first case showed no clinical improvement after 15 days of treatment. The second case showed a mild improvement of the initial lesion. In conclusion, treatment with tracolimus, pentoxifylline, and prednisonole appears to have a good effect in mild and early lesions. The objective of this paper was to describe the clinical findings, treatment options and histopathological aspects in two Brazilian Mastiff dogs, not previously reported.
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Search related cases →Original publication on Crossref: https://doi.org/10.24070/bjvp.1983-0246.v10i2p47-51