Peer-reviewed veterinary case report
Dog with bladder histiocytic sarcoma lived over 2 years
By Patten, Steve & MacKenzie, Shawn·Published in Journal of the American Animal Hospital Association·2022·From the Oncology Department (S.P.), Canada·View original on PubMed →
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Original publication title: Prolonged Survival Following Treatment of Histiocytic Sarcoma of the Canine Urinary Bladder.
- Species:
- dog
Plain-English summary
A 9-year-old male miniature schnauzer was diagnosed with a rare type of cancer called histiocytic sarcoma in the urinary bladder. After surgery, the dog received chemotherapy treatments, starting with lomustine, which had to be stopped due to side effects, and then doxorubicin. The dog responded well to both treatments, and after finishing the doxorubicin, he showed no signs of cancer for over two years. This case is notable because it shows a much longer survival compared to previous reports of this condition.
People also search for: dog urinary bladder cancer treatment · miniature schnauzer histiocytic sarcoma · doxorubicin for dog cancer
Abstract
A 9 yr old castrated male miniature schnauzer was diagnosed histopathologically with a mucosal histiocytic sarcoma of the urinary bladder apex, biopsied at the time of surgical cystotomy. Sequential adjuvant chemotherapy, including both lomustine (discontinued because of adverse effects) and then doxorubicin, were employed. A response to both agents was documented. Ultimately, a complete response was achieved following completion of the doxorubicin protocol. A complete response persisted 768 days following diagnosis at last follow-up. Histiocytic sarcoma of the urinary bladder remains a rare diagnosis in veterinary medicine. Only one previous case report is currently published. This case contrasts with the previous case report, which reported a survival of only 2 mo.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/35576399/