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Peer-reviewed veterinary case report

Prophylactic allergen immunotherapy with Der p 2 prevents murine asthma by regulating lung GM-CSF.

Journal:
The Journal of allergy and clinical immunology
Year:
2019
Authors:
Haspeslagh, Eline et al.
Affiliation:
Department of Internal Medicine and Pediatrics

Abstract

This mouse study demonstrates that repetitive inhalation of a single major house dust mite (HDM) allergen prevents HDM-induced allergic asthma development through suppressing the function of lung dendritic cells, thus providing an alternative to classical allergen-specific immunotherapy.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/30796980/