Peer-reviewed veterinary case report
Horse very tired after anesthesia - is dantrolene the cause?
By Valverde, A et al.·Published in Journal of the American Veterinary Medical Association·1990·Department of Clinical Studies, Canada·View original on PubMed →
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Original publication title: Prophylactic use of dantrolene associated with prolonged postanesthetic recumbency in a horse.
- Species:
- horse
Plain-English summary
In this study, a horse was given dantrolene, a medication that helps prevent a serious condition called malignant hyperthermia, before undergoing anesthesia. The idea was to stop the horse from developing muscle problems after waking up from the anesthesia. However, it was found that giving dantrolene beforehand led to the horse staying down for a longer time than usual after the procedure. While dantrolene can be helpful, it may also cause side effects like unsteady movements. Overall, the use of dantrolene in this case resulted in the horse being down longer than expected after anesthesia.
Abstract
Dantrolene, a drug used in the prevention and treatment of malignant hyperthermia, was believed responsible for prolonged postanesthetic recumbency in a horse. Prophylactically, dantrolene was given orally before induction of anesthesia. Dantrolene has been recommended for use in horses at risk of developing postanesthetic myopathy. Side effects, including ataxia, may result from dantrolene administration.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/2243040/