Peer-reviewed veterinary case report
Dog developed muscle breakdown and heart issues from propofol infusion
By Mallard, John M et al.·Published in The Canadian veterinary journal = La revue veterinaire canadienne·2018·Department of Emergency and Critical Care, United States·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Propofol infusion-like syndrome in a dog.
- Species:
- dog
Plain-English summary
An 8-year-old spayed female Chihuahua was brought in for breathing problems and needed help with a ventilator. During her treatment, she developed serious issues like muscle breakdown, dark urine, heart rhythm problems, and liver damage after receiving a medication called propofol. The vet stopped the propofol and gave her a medication called N-acetylcysteine, which helped her recover. After treatment, her symptoms improved and she was able to breathe normally again.
People also search for: dog breathing problems · Chihuahua propofol side effects · N-acetylcysteine for dogs
Abstract
An 8-year-old, spayed female Chihuahua mixed breed dog was presented for dyspnea and was subsequently mechanically ventilated. Propofol was utilized as part of the anesthetic protocol. The dog developed rhabdomyolysis, myoglobinuria, cardiac arrhythmias, liver enzyme elevation, and methemoglobinemia. Propofol was discontinued and N-acetylcysteine was administered after which the clinical signs resolved.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/30410181/