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Peer-reviewed veterinary case report

Proposed limits for ordinal echocardiographic estimates of left atrial enlargement in dogs.

Journal:
Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology
Year:
2023
Authors:
Rishniw, M
Affiliation:
Department of Clinical Sciences · United States
Species:
dog

Abstract

OBJECTIVE: To propose echocardiographic left-atrial-to-aortic ratio&#xa0;(LA:Ao) limits for defining ordinal categories of left atrial (LA) enlargement in dogs. ANIMALS, MATERIALS AND METHODS: Right parasternal short-axis echocardiographic images from 33 dogs with various degrees of LA enlargement. Right parasternal short-axis and long-axis echocardiographic measurements from 238 healthy dogs. Images were duplicated and randomized. Duplicate images contained a LA:Ao estimate. Participants categorized the LA in each image into one of four categories: normal, mildly, moderately or severely enlarged. Distributions of categorization were compared between cardiologists and non-cardiologists. Intra-observer intra-study and inter-study agreement were examined. Effect of measurement was evaluated on agreement between participants. A parametric estimate of LA enlargement was calculated for both short-axis and long-axis views. RESULTS: Cardiologists and non-cardiologists provided similar distributions of LA size&#xa0;estimates, and showed similarly high intra-observer agreement (kappa&#xa0;=&#xa0;0.84). Having a measurement provided with the image increased agreement for categorizing LA as normal or mildly enlarged (P<0.001). Parametric and&#xa0;consensus-based approaches provided similar limits for categorizing left atrial&#xa0;size in the right parasternal short-axis view - normal&#xa0;=&#xa0;LA:Ao&#xa0;<&#xa0;1.6, mildly enlarged&#xa0;=&#xa0;1.6&#xa0;<&#xa0;LA:Ao&#xa0;<&#xa0;1.9, moderately enlarged&#xa0;=&#xa0;1.9&#xa0;<&#xa0;LA:Ao&#xa0;<&#xa0;2.3, severely enlarged&#xa0;=&#xa0;LA:Ao&#xa0;&#x2265;&#xa0;2.3. A parametric approach for the right parasternal long-axis view provided the following: normal&#xa0;=&#xa0;LA:Ao&#xa0;<&#xa0;2.1, mildly enlarged&#xa0;=&#xa0;2.1&#xa0;<&#xa0;LA:Ao&#xa0;<&#xa0;2.5, moderately enlarged&#xa0;=&#xa0;2.5&#xa0;<&#xa0;LA:Ao&#xa0;<&#xa0;2.7, severely enlarged&#xa0;=&#xa0;LA:Ao&#xa0;&#x2265;&#xa0;2.7. CONCLUSIONS: Participants mostly classified LA sizes into four ordinal categories that corresponded to the aforementioned limits. Clinicians estimating LA size in early diastole can use these limits to increase inter-observer agreement when identifying LA enlargement.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/37141841/