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Peer-reviewed veterinary case report

Ciclosporin helps reduce itching in cats with allergic skin disease

By Noli, C & Scarampella, F·Published in The Journal of small animal practice·2006·Ospedale Veterinario Cuneese, Italy·View original on PubMed

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Original publication title: Prospective open pilot study on the use of ciclosporin for feline allergic skin disease.

Species:
cat
Skin & coatCats

Plain-English summary

Ten cats with allergic skin issues, like itching and red skin, were treated with a medication called ciclosporin for a month. These cats had not improved with a special diet or other treatments before starting the trial. After the treatment, about 40% showed good improvement in itching, while 57% had better fur growth, and 60% had less redness. Although ciclosporin is not officially approved for use in cats, it may help manage symptoms of allergic skin disease.

People also search for: cat itching treatment · ciclosporin for cat skin problems · allergic skin disease in cats

Abstract

OBJECTIVES: To evaluate the efficacy of ciclosporin in cats with allergic skin disease. METHODS: Ten cats with signs of allergic skin disease were administered ciclosporin daily at a dose of 3.6 to 8.3 mg/kg for one month. None of these cats had previously responded to a hypoallergenic diet trial, and all animals had previously been treated with endectoparasiticidal drugs, with no improvement two weeks before entering the trial. On days 0 and 30, owners assessed pruritus with a visual analogue scale, and veterinarians evaluated cutaneous lesions. RESULTS: All the cats had pruritus and erythema, five had alopecia, two had an eosinophilic plaque, one had miliary dermatitis and two had both alopecia and an eosinophilic plaque. Good or excellent improvement was observed in 40 per cent of cats for pruritus, 57 per cent of cats for alopecia and 60 per cent of cats for erythema. A significant decrease in mean scores was observed for pruritus only, while for erythema and alopecia, it was close to being significant (P < 0.052). CLINICAL SIGNIFICANCE: Ciclosporin may be helpful in symptomatically treating signs of feline allergic skin disease. However, it is important to remember that ciclosporin is not licensed for use in cats.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/16911110/