Peer-reviewed veterinary case report
Prostaglandin Ainhibits the replication of bovine viral diarrhea virus.
- Journal:
- Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]
- Year:
- 2018
- Authors:
- Caldas, Lúcio Ayres et al.
- Affiliation:
- Instituto Nacional de Metrologia · Brazil
Abstract
Bovine viral diarrhea virus can cause acute disease in livestock, leading to economic losses. We show that Prostaglandin Ainhibits bovine viral diarrhea virus replication in Madin-Darby bovine kidney cells (94% inhibition using 5μg/mL). Light and electron microscopy of infected cells shows that Prostaglandin Aalso prevents virus-induced vacuolization, but at higher concentrations (10μg/mL).
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/29544983/