Peer-reviewed veterinary case report
Dog straining to pee and poop due to prostate tumor
By Trovatelli, Marco et al.·Published in Journal of veterinary internal medicine·2021·Department of Veterinary Medicine, Italy·View original on PubMed →
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Original publication title: Prostatic leiomyosarcoma in a dog treated using a multimodal approach.
- Species:
- dog
Plain-English summary
A 12-year-old male German Wirehaired Pointer was brought in because he was having trouble straining to defecate and urinate. A CT scan revealed a large tumor in his prostate, which was confirmed to be prostatic leiomyosarcoma (a type of cancer). The vet performed surgery to remove part of the prostate and then treated him with chemotherapy using metronomic cyclophosphamide and anti-inflammatory medications. After 15 months, follow-up scans showed no signs of the cancer coming back, marking a successful treatment outcome.
People also search for: dog prostate cancer treatment · German Wirehaired Pointer straining to urinate · prostatic leiomyosarcoma in dogs
Abstract
Prostatic leiomyosarcoma is an uncommon tumor encountered in male dogs, with only 2 cases reported in the veterinary literature with no follow-up described. A 12-year-old male intact German Wirehaired Pointer presented for evaluation of straining to defecate and urinate. Whole body computed tomography (CT) examination identified a spherical multicavitary expansile mass arising from the prostate gland and severely obliterating the pelvic canal. Partial subcapsular prostatectomy was performed, and histological and immunohistochemical results were consistent with prostatic leiomyosarcoma. Metronomic cyclophosphamide and nonsteroidal anti-inflammatory drugs were administered as adjuvant chemotherapy. Follow-up CT 10 months later indicated no signs of recurrence or metastasis. To the best of our knowledge, this patient represents the first report of successful multidisciplinary treatment consisting of partial subcapsular prostatectomy and adjuvant chemotherapy for prostatic leiomyosarcoma in a dog. After 15 months of follow-up, the patient remained recurrence-free without metastasis.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/33625746/