Peer-reviewed veterinary case report
Dog with prostate cancer causing trouble urinating and bleeding
By Pinto da Cunha, Nazarél et al.·Published in Veterinary clinical pathology·2007·Departimento di Patologia Animale, Italy·View original on PubMed →
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Original publication title: Prostatic sarcomatoid carcinoma in a dog: cytologic and immunohistochemical findings.
- Species:
- dog
Plain-English summary
An 8-year-old neutered male Boxer was brought to the vet with symptoms of straining to urinate, blood in his urine, and difficulty passing urine. Tests showed that his prostate was enlarged and irregular. Surgery revealed a mass in the prostate, which was found to be a rare type of cancer called prostatic sarcomatoid carcinoma. Unfortunately, the cancer had spread to nearby tissues, and despite the diagnosis, the prognosis was poor.
People also search for: Boxer dog blood in urine · dog prostate cancer symptoms · treatment for dog urinary issues
Abstract
An 8-year-old neutered male Boxer was presented with tenesmus, hemorrhagic urethral discharge, and dysuria. Abdominal ultrasound and radiographic examinations revealed irregular prostatic enlargement. Laparotomy was performed and intraoperative cytology was done on imprint smears of a biopsy specimen obtained from a prostatic mass. The cytologic preparation was highly cellular and contained a predominant population of atypical, large, loosely cohesive spindle cells, with rare multinucleated cells and mitotic figures. The cytologic findings were consistent with undifferentiated sarcoma. At necropsy, a large cystic prostatic mass and numerous satellite nodules in the soft tissues around the pelvis were found. On histologic examination the tumor was composed primarily of bundles of neoplastic spindle cells. Rare pseudo-acinar structures and signet-ring cells also were observed. On immunohistochemical examination, the neoplastic cells co-expressed cytokeratin and vimentin. Based on histologic and immunohistochemical findings, the tumor was diagnosed as primary prostatic sarcomatoid carcinoma. This is a rare tumor in dogs, in which biphasic morphology of epithelial and mesenchymal cells can complicate the diagnosis, requiring immunochemical stains for confirmation.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/18041705/