Peer-reviewed veterinary case report
Cat vaccine protects against feline leukemia virus for 2 years
By Jirjis, Faris F et al.·Published in Veterinary therapeutics : research in applied veterinary medicine·2010·Intervet/Schering-Plough Animal Health, United States·View original on PubMed →
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Original publication title: Protection against feline leukemia virus challenge for at least 2 years after vaccination with an inactivated feline leukemia virus vaccine.
- Species:
- cat
Plain-English summary
Twelve kittens were vaccinated against feline leukemia virus (FeLV) at 8 and 11 weeks old, while eleven other kittens received a placebo. After two years in isolation, the vaccinated kittens were exposed to the virus to see if the vaccine worked. The results showed that 83% of the vaccinated kittens remained protected from the virus, while all of the control kittens developed the disease. This study suggests that the inactivated FeLV vaccine can provide protection for at least two years after vaccination.
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Abstract
Twelve cats were vaccinated at 8 and 11 weeks of age with a commercially available inactivated FeLV vaccine (Nobivac FeLV, Intervet/Schering-Plough Animal Health). Eleven cats served as age-matched, placebo-vaccinated controls. All cats were kept in isolation for 2 years after vaccination and were then challenged with virulent FeLV to evaluate vaccine efficacy and duration of immunity. Cats were monitored for 12 weeks after challenge for development of persistent viremia using a commercial FeLV p27 ELISA. Persistent viremia developed in all 11 (100%) of the control cats, whereas 10 of 12 (83%) vaccinated cats were fully protected from persistent viremia following challenge. The results demonstrate that the vaccine used in this study protects cats from persistent FeLV viremia for at least 2 years after vaccination.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/20957616/