Peer-reviewed veterinary case report
Protective Efficacy of Lyophilized Vesicular Stomatitis Virus-Based Vaccines in Animal Model.
- Journal:
- Emerging infectious diseases
- Year:
- 2024
- Authors:
- Salawudeen, Abd'jeleel et al.
- Species:
- rodent
Abstract
We evaluated the in vitro effects of lyophilization for 2 vesicular stomatitis virus-based vaccines by using 3 stabilizing formulations and demonstrated protective immunity of lyophilized/reconstituted vaccine in guinea pigs. Lyophilization increased stability of the vaccines, but specific vesicular stomatitis virus-based vaccines will each require extensive analysis to optimize stabilizing formulations.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/38666640/