Peer-reviewed veterinary case report
Protein and antibody levels in urine of newborn Rottweiler puppies
By Schäfer-Somi, S et al.·Published in The Veterinary record·2005·University Clinic for Obstetrics·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Proteinuria and immunoglobulinuria in neonatal dogs.
- Species:
- dog
Plain-English summary
A group of 45 newborn Rottweiler puppies had their urine tested for protein levels and immunoglobulins (antibodies) shortly after birth. Initially, the puppies showed higher than normal protein levels in their urine, but these levels decreased significantly over the first two weeks. Despite the initial findings, all the puppies grew and developed normally, with many showing measurable levels of certain antibodies by the end of the two weeks. This suggests that while the puppies had some early urinary abnormalities, they did not affect their overall health or development.
People also search for: Rottweiler puppy urine protein levels · newborn puppy health issues · puppy immunoglobulin levels
Abstract
Samples of urine and serum from 45 newborn rottweiler puppies from six litters, and milk from their mothers, were taken 24, 48 and 72 hours and seven and 14 days after birth. Urine total protein and creatinine concentrations were determined and the ratios calculated. The immunoglobulin (Ig) concentrations of IgG, IgM and IgA in urine, serum and milk were determined with a commercially available elisa kit. The concentration of total protein in urine decreased from 1.64 to 0.29 mg/ml, and it and the ratio of total protein to creatinine in the urine of the neonatal puppies exceeded the normal values for adult dogs, but all the puppies developed normally. The average concentration of IgG in urine decreased from 0.0035 to 0.0003 mg/ml, that of IgA from 0.0035 to 0.0002 mg/ml and that of IgM from 0.0006 mg/ml to undetectable levels after two weeks. After two weeks, 47 per cent of the puppies had measurable levels of IgA and 70.6 per cent had measurable levels of IgG, but none of them had measurable levels of IgM.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/16183897/