Peer-reviewed veterinary case report
Proteomic analysis of hypertrophied myocardial protein patterns in renovascularly hypertensive and spontaneously hypertensive rats.
- Journal:
- Journal of proteome research
- Year:
- 2006
- Authors:
- Zhou, Si-Gui et al.
- Affiliation:
- Pharmacology and Toxicology Laboratory and Institute of Clinical Pharmacology · China
- Species:
- rodent
Abstract
The cardiac protein profiles of spontaneously hypertensive and renovascularly hypertensive hypertrophy showed a significant alteration compared with normal hearts. Most proteins with significant modulations in their expressions belong to the category of metabolic and stress-related proteins. Among these proteins, glutathione-S-transferase mu2 and short-chain acyl-CoA dehydrogenase may be two candidate proteins associated with left ventricular hypertrophy in spontaneously hypertensive rats.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/17081041/