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Peer-reviewed veterinary case report

Proteomic analysis of porcine saliva.

Journal:
Veterinary journal (London, England : 1997)
Year:
2011
Authors:
Gutiérrez, A M et al.
Affiliation:
Department of Animal Medicine and Surgery · Spain

Abstract

Saliva contains a number of proteins that may be useful as biomarkers of health and disease and can be easily obtained from large numbers of animals in a non-invasive, stress-free way. The objective of this study was to explore the protein composition of porcine saliva from 10 specific pathogen free pigs using first one-dimensional SDS-PAGE and then two-dimensional electrophoresis and mass spectrometry. A reference proteome pattern for porcine saliva was established with the identification of 13 different, mainly saliva-specific, proteins. These reference data will facilitate the investigation of salivary proteins potentially altered in disease and could serve as novel diagnostic biomarkers.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/20093058/