Peer-reviewed veterinary case report
Protocol for establishing a mouse model of bilateral maxillary first molar extraction to study alveolar bone healing.
- Journal:
- STAR protocols
- Year:
- 2026
- Authors:
- Jiang, Jiarui et al.
- Affiliation:
- School of Stomatology · China
Abstract
Alveolar bone healing following tooth extraction is a complex biological process. Here, we present a protocol for establishing a reproducible mouse model of bilateral maxillary first molar extraction to study alveolar bone healing. We describe steps for surgery, postoperative care, and tissue collection for downstream genomic, histological, and micro-computed tomography (CT) analyses. We provide practical strategies to minimize root fracture and soft tissue injury, ensuring procedural consistency and high-quality outcomes.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/41701575/