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Peer-reviewed veterinary case report

Protocol for hydroxylating aryl chlorides catalyzed by photouranium with water under ambient conditions.

Year:
2024
Authors:
Li C et al.
Affiliation:
Hainan Institute of East China Normal University · China

Abstract

Here, we present a protocol for the hydroxylation of aryl chlorides catalyzed by photouranium with water under ambient conditions. We describe steps for gram-scale hydroxylation of 2'-chloroacetophenone using our self-designed continuous-flow photoreactor. We then detail procedures for obtaining 2'-hydroxyacetophenone using our self-designed rapid separation and purification instrument. This protocol is not suitable for polycyclic and heterocyclic aryl chlorides. For complete details on the use and execution of this protocol, please refer to Sun et al.<sup>1</sup>.

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Original publication: https://europepmc.org/article/MED/39340777