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Peer-reviewed veterinary case report

Protocol to record and quantify absence seizures in rats using EEG arrays.

Journal:
STAR protocols
Year:
2025
Authors:
Buller-Peralta, Ingrid et al.
Affiliation:
Institute for Neuroscience and Cardiovascular Research · United Kingdom
Species:
rodent

Abstract

We present a protocol for implanting 32-channel NeuroNexus skull-surface electroencephalogram (EEG) arrays in rats to record absence seizure-like events. We describe steps for surgical implantation and automated offline detection of seizures from Open Ephys EEG recordings. This approach enables brain-wide, multi-day electrophysiological monitoring to assess epilepsy and seizure dynamics in rodents. For complete details on the use and execution of this protocol, please refer to Katsanevaki et al..

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Original publication: https://pubmed.ncbi.nlm.nih.gov/41175369/