Peer-reviewed veterinary case report
Vomiting and duodenal perforation in dogs after deracoxib use
By Case, J Brad et al.·Published in Journal of the American Animal Hospital Association·2010·Department of Surgery, United States·View original on PubMed →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Proximal duodenal perforation in three dogs following deracoxib administration.
- Species:
- dog
Plain-English summary
Three dogs developed serious stomach problems after starting treatment with a pain medication called deracoxib. They showed symptoms like sudden vomiting and loss of appetite. When vets performed surgery, they found holes in the dogs' intestines, which can lead to severe infections. Out of the three dogs, two recovered after surgery. This case highlights the importance of closely monitoring dogs for any signs of gastrointestinal issues when they are on deracoxib, even at the recommended doses.
People also search for: dog vomiting after medication · deracoxib side effects in dogs · dog intestinal perforation treatment
Abstract
The purpose of this study was to describe the clinical and gross pathological findings, treatment, and outcome in three dogs receiving deracoxib that developed proximal duodenal perforation and subsequent septic peritonitis. Clinical findings were acute vomiting and anorexia following initiation of deracoxib therapy. Deracoxib dosages ranged from 2 to 3 mg/kg per os q 24 hours. In each dog, exploratory laparotomy revealed duodenal perforations approximately 1 cm orad to the major duodenal papilla. Two out of three dogs survived following exploratory laparotomy. Two of three dogs in the present case series received the approved deracoxib dosage. Dogs receiving deracoxib, even at labeled dosages, should be monitored judiciously for signs of gastrointestinal disease.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/20610698/