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Peer-reviewed veterinary case report

Pseudo-placentational endometrial hyperplasia in a dog.

Journal:
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc
Year:
2011
Authors:
Sato, Yoshihiko
Affiliation:
SATO Animal Clinic · Japan
Species:
dog

Plain-English summary

A 9.5-month-old female dog that was healthy and not pregnant or experiencing a false pregnancy underwent surgery to remove her ovaries and uterus. During the surgery, the veterinarian found a swollen area in her uterus that was about 3 centimeters wide and filled with a lot of fluid. The inner lining of this part of the uterus had many small, yellowish-white growths. Further examination of the tissue showed that the lining was thickened and the glands inside were stretched, resembling changes that happen in a pregnant dog, even though she wasn't pregnant. This condition is called pseudo-placentational endometrial hyperplasia, and it was diagnosed as a spontaneous occurrence in this young dog.

Abstract

Ovariohysterectomy in a healthy, nonpregnant, non-pseudopregnant, 9.5-month-old female dog revealed a 3 cm in diameter, swollen segmental portion of the uterus. A large amount of mucoserous fluid was present in the segmental portion, and the mucous membrane was covered by many yellowish-white villi protruding into the lumen. Histopathologic examination revealed endometrial hyperplasia associated with dilatation of the uterine glands in the segmental portion. The morphological findings were quite similar to those of a maternal placenta of pregnancy without the fetus and fetal membrane. Accordingly, this young female dog was diagnosed with spontaneous pseudo-placentational endometrial hyperplasia.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/21908378/