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Peer-reviewed veterinary case report

Dog with rare pseudoangiomatous oral squamous cell carcinoma

By Cushing, Tim et al.·Published in Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·2010·Cornell University College of Veterinary Medicine, United States·View original on PubMed

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Original publication title: Pseudoangiomatous squamous cell carcinoma in the oral cavity of a dog.

Species:
dog

Plain-English summary

An 8-year-old spayed female Labrador Retriever was brought to the vet because of an invasive mass in her mouth near her upper teeth. Initial tests suggested it was a type of cancer called squamous cell carcinoma, but further examination revealed it was a rare variant known as pseudoangiomatous squamous cell carcinoma. This type of tumor can look similar to other growths in the mouth, so it's important for vets to recognize it as a possibility. The dog underwent surgery to remove the mass, which is a common treatment for oral tumors in dogs.

People also search for: dog oral mass treatment · Labrador Retriever mouth cancer · squamous cell carcinoma in dogs

Abstract

An 8-year-old, spayed, female Labrador Retriever mixed-breed dog was presented to the Cornell University Hospital for Animals with an invasive oral mass involving the upper left fourth premolar and first molar teeth. Initial biopsy results suggested a poorly differentiated squamous cell carcinoma, whereas further histologic examination of the surgically removed mass revealed a hemangiosarcoma-like mass composed of numerous vascular clefts and variable numbers of keratinizing epithelial cells. Histologic and immunohistochemical characteristics were compatible with pseudoangiomatous squamous cell carcinoma, a well-recognized human variant of acanthomatous squamous cell carcinoma. Because of histomorphologic similarities with canine gingival hemangiosarcoma, diagnosticians should be aware of the present tumor variant as a differential diagnosis for vascular-like growths in the oral cavity of dogs.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/20224097/