Peer-reviewed veterinary case report
Pseudorabies Virus Fast Axonal Transport Occurs by a pUS9-Independent Mechanism.
- Journal:
- Journal of virology
- Year:
- 2015
- Authors:
- Daniel, Gina R et al.
- Affiliation:
- Department of Microbiology-Immunology · United States
Abstract
Reactivation from latency results in transmission of neurotropic herpesviruses from the nervous system to body surfaces, referred to as anterograde axonal trafficking. The virus-encoded protein pUS9 promotes axonal dissemination by sorting virus particles into axons, but whether it is also an effector of fast axonal transport within axons is unknown. To determine the role of pUS9 in anterograde trafficking, we analyzed the axonal transport of pseudorabies virus in the presence and absence of pUS9.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/25995254/