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Peer-reviewed veterinary case report

Pulmonary atresia with dextroposition of the aorta and ventricular septal defect in three Arabian foals.

Journal:
Veterinary pathology
Year:
1982
Authors:
Vitums, A & Bayly, W M
Species:
horse

Plain-English summary

Three male Arabian foals were brought in because they were showing signs of a serious heart problem, including a bluish color to their skin, a heart murmur, and difficulty exercising. After examining them, the veterinarians suspected that they had a condition called a ventricular septal defect (a hole in the heart) along with other heart malformations. Unfortunately, the prognosis was very poor, and the owners chose to have the foals euthanized. During the examination after death, it was found that all three foals had similar heart defects, including a large hole in the heart and abnormal connections of the blood vessels. Sadly, the treatment options were not effective, leading to the decision to euthanize the foals.

Abstract

Three Arabian males foals were presented with cyanosis, heart murmur, and exercise intolerance, Results of clinical evaluation suggested a tentative diagnosis of ventricular septal defect in conjunction with malformations of the great arteries. Each foal had a poor prognosis and was killed at the owners' requests. At necropsy, the malformed hearts of the three foals were virtually identical. Each heart had a large defect in the upper interventricular septum. The aorta originated from the hypertrophied right ventricle and partially overrode the ventricular septal defect. The aortic ostium was guarded by three semilunar valvules. The position of the valvules and the ostia of the coronary arteries was abnormal. The pulmonary arteries arose from the persistent ductus arteriosus. The pulmonary trunk was reduced to a thin, fibrous cord extending from a short and narrow persistent ductus arteriosus to the level of the semilunar valve, where it fused with the wall of the aorta. No communication of the atretic pulmonary trunk with the cavity of the right ventricle was seen.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/7072088/