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Peer-reviewed veterinary case report

Cat with coughing diagnosed with lung carcinosarcoma tumor

By Ghisleni, Gabriele et al.·Published in Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·2003·Dipartimento di Patologia Animale, Italy·View original on PubMed

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Original publication title: Pulmonary carcinosarcoma in a cat.

Species:
cat
Breathing & coughCats

Plain-English summary

A Domestic Shorthaired cat was brought in for coughing and severe breathing problems. X-rays showed a large mass in the lungs along with other smaller masses. Unfortunately, the cat was euthanized, and further examination revealed a rare type of lung cancer called pulmonary carcinosarcoma, which is a mix of two different cancer types. This type of tumor is uncommon in pets and had not been previously reported in cats.

People also search for: cat coughing treatment · cat breathing problems · lung cancer in cats · pulmonary carcinosarcoma in cats

Abstract

A Domestic Shorthaired cat was presented with coughing and severe respiratory distress. Thoracic radiographs revealed a lobar mass and numerous additional cavitated intrapulmonary masses. The cat was euthanized and submitted for necropsy. Histological examination of the large mass revealed 2 distinct neoplastic components consisting of bronchial adenocarcinoma admixed with neoplastic areas composed of highly atypical undifferentiated spindle cells (sarcomatous component). Simultaneous expression of vimentin and cytokeratin by a subpopulation of neoplastic epithelial cells and by rare neoplastic spindle cells was identified. On the basis of histology and immunohistochemical results, a diagnosis of primary pulmonary carcinosarcoma with intrapulmonary epithelial metastases was made. Pulmonary carcinosarcoma is a well-known pathological entity in humans. It is a rare tumor in animals and has not been previously reported in cat.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/12661729/