Peer-reviewed veterinary case report
Pulmonary fibrosis in horses associated with spontaneous Crotalaria juncea intoxication.
- Journal:
- Toxicon : official journal of the International Society on Toxinology
- Year:
- 2026
- Authors:
- Andrade, Andrezza C et al.
- Affiliation:
- Laborató · Brazil
- Species:
- horse
Abstract
We report an outbreak of Crotalaria juncea intoxication in horses exhibiting progressive weight loss and respiratory distress in northeastern Brazil. Necropsy revealed firm, non-collapsed lungs with extensive interstitial fibrosis, bronchiolar epithelial hyperplasia with club cells proliferation, and marked pulmonary arterial remodeling. Hepatic lesions consisted primarily of centrilobular necrosis, probably resulting from hypoxic injury related to anemia and prolonged agonic death. Pasture inspection identified significant invasion by shrubs of C. juncea in various phenological stages.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/41740763/