Peer-reviewed veterinary case report
Lung cancer causing cough and appetite loss in a Beagle dog
By Michishita, Masaki et al.·Published in Journal of comparative pathology·2023·Department of Veterinary Pathology, Japan·View original on PubMed →
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Original publication title: Pulmonary solid adenocarcinoma in a dog.
- Species:
- dog
Plain-English summary
A 12-year-old male Beagle was brought in because he had been losing his appetite and coughing for a month. After further examination, scans showed serious issues in his lungs, and tests indicated he had a type of lung cancer called pulmonary solid adenocarcinoma. Unfortunately, despite the veterinary team's efforts, the dog's condition worsened, leading to his euthanasia due to severe breathing problems and decreased activity.
People also search for: dog coughing and not eating · Beagle lung cancer symptoms · treatment for dog lung tumors
Abstract
A 12-year-old castrated male Beagle dog presented with a 1-month history of progressive loss of appetite and cough. One month after the initial visit, a detailed clinical examination was performed due to weight loss and persistent cough. Computed tomography demonstrated diffuse opacification of the entire right lung and cranial lobe of the left lung. Samples of the pulmonary lesions obtained by fine-needle aspiration (FNA) were highly cellular with scattered and clustered foci of large round cells, suggestive of a round cell tumour. Ten days after the FNA, the dog was euthanized due to decreased activity and severe respiratory symptoms. At necropsy, enlargement of the entire right lung and cranial lobe of the left lung was seen. The external and cut surfaces of the lungs were homogeneously grey-white. Histopathological examination of sections of the right lung and the cranial lobe of the left lung revealed proliferation of large round or polygonal neoplastic cells arranged in nests of variable size separated by a thin fibrous stroma. Neoplastic cells were immunopositive for cytokeratin and thyroid transcription factor-1 but negative for vimentin, CD204, chromogranin A and synaptophysin. On the basis of these findings, the tumour was diagnosed as pulmonary solid adenocarcinoma.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/36758478/