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Peer-reviewed veterinary case report

Survival and risk factors for pulmonic stenosis in dogs

By Locatelli, C et al.·Published in The Journal of small animal practice·2013·Dipartimento di Scienze Veterinarie e Salute Pubblica, Italy·View original on PubMed

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Original publication title: Pulmonic stenosis in dogs: survival and risk factors in a retrospective cohort of patients.

Species:
dog

Plain-English summary

A group of dogs with a heart condition called pulmonic stenosis (narrowing of the heart valve) was studied to understand their survival rates and risk factors. Symptoms like difficulty breathing or fainting were linked to a higher risk of poor outcomes, especially in younger dogs and those with a specific type of valve issue. Dogs that underwent a procedure called pulmonary balloon valvuloplasty had better chances of survival, particularly if they were severely affected or showed no symptoms at all. Overall, treatment options like this procedure can significantly improve the quality of life for dogs with this condition.

People also search for: dog heart problems treatment · pulmonic stenosis in dogs · balloon valvuloplasty for dogs · symptoms of heart disease in dogs

Abstract

OBJECTIVES: To assess survival and risk factors in dogs with pulmonic stenosis. METHODS: A retrospective review of medical case records of all cases of pulmonic stenosis >50 mmHg, undergoing pulmonary balloon valvuloplasty or not. Survival curves and multivariate analysis were calculated in the overall population and in subgroups. RESULTS: One hundred and seventy-two cases were included. Factors negatively affecting survival were clinical signs [hazard ratio (HR) 3&#x2009;&#xb7;&#x2009;44, P&#x2009;<&#x2009;0&#x2009;&#xb7;&#x2009;001], younger age at diagnosis (HR 3&#x2009;&#xb7;&#x2009;96, P&#x2009;=&#x2009;0&#x2009;&#xb7;&#x2009;001) and valve morphology type B (HR 3&#x2009;&#xb7;&#x2009;33, P&#x2009;=&#x2009;0&#x2009;&#xb7;&#x2009;001) in the overall population. In those that had pulmonary balloon valvuloplasty group only clinical signs was significant (HR 3&#x2009;&#xb7;&#x2009;44, P&#x2009;<&#x2009;0&#x2009;&#xb7;&#x2009;001). In cases that did not undergo pulmonary balloon valvuloplasty group Doppler gradient (HR 1&#x2009;&#xb7;&#x2009;02, P&#x2009;<&#x2009;0&#x2009;&#xb7;&#x2009;001), clinical signs (HR 5&#x2009;&#xb7;&#x2009;41, P&#x2009;=&#x2009;0&#x2009;&#xb7;&#x2009;002), valve morphology type B (HR 10&#x2009;&#xb7;&#x2009;20, P&#x2009;=&#x2009;0&#x2009;&#xb7;&#x2009;001) and younger age at diagnosis (HR 12&#x2009;&#xb7;&#x2009;82, P&#x2009;<&#x2009;0&#x2009;&#xb7;&#x2009;001) negatively affected survival. Dogs with severe pulmonic stenosis undergoing pulmonary balloon valvuloplasty (HR 0&#x2009;&#xb7;&#x2009;47, P&#x2009;=&#x2009;0&#x2009;&#xb7;&#x2009;047) and asymptomatic dogs with moderate pulmonic stenosis (HR 0&#x2009;&#xb7;&#x2009;10, P&#x2009;=&#x2009;0&#x2009;&#xb7;&#x2009;042) had a better outcome. Younger age at diagnosis was correlated with poorer outcome in right-sided congestive heart failure dogs (HR 14&#x2009;&#xb7;&#x2009;02, P&#x2009;=&#x2009;0&#x2009;&#xb7;&#x2009;01). CLINICAL SIGNIFICANCE: Clinical signs, valve morphology type B and age at diagnosis are risk factors in pulmonic stenosis patients. Pulmonary balloon valvuloplasty is a reasonable treatment choice in dogs with severe pulmonic stenosis.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23889710/