Peer-reviewed veterinary case report
Punctal stenosis causing watery eyes in 6 dogs after long-term eye
By Quantz, Katelin & Stiles, Jean·Published in Veterinary ophthalmology·2019·Department of Veterinary Clinical Sciences·View original on PubMed →
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Original publication title: Punctal stenosis in 6 dogs following the long-term use of topical neomycin-polymyxin B-dexamethasone.
- Species:
- dog
Plain-English summary
Six dogs developed a condition called punctal stenosis, which is a narrowing of the tear duct openings, after using a specific eye medication containing neomycin, polymyxin B, and dexamethasone for a long time. These dogs were initially brought in for various eye problems that required ongoing treatment. Symptoms included excessive tearing, known as epiphora, and the diagnosis was confirmed by observing scar tissue around the tear ducts. Treatment options for these dogs were not detailed, but it's important for pet owners to discuss any concerns about long-term eye medication with their veterinarian to prevent similar issues.
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Abstract
Six dogs were diagnosed with punctal stenosis following the long-term use of topical neomycin-polymyxin B-dexamethasone (NPD). All patients were initially presented for ophthalmic diseases requiring ongoing anti-inflammatory therapy. Five of the 6 dogs had previously or concurrently been treated with topical anti-inflammatory medications other than NPD. One patient exclusively received topical NPD prior to the diagnosis of punctal stenosis. The onset of punctal stenosis following therapy with NPD was variable among patients, ranging from 4 months to over 1 year. Diagnosis of punctal stenosis was made based upon the presence of epiphora and visualization of fibrotic tissue over the nasolacrimal puncta.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/30211477/