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Peer-reviewed veterinary case report

Dog developed pemphigus foliaceus after ketoconazole shampoo use

By Sung, Hyun-Jeong et al.·Published in The Canadian veterinary journal = La revue veterinaire canadienne·2017·Department of Veterinary Internal Medicine, South Korea·View original on PubMed

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Original publication title: Putative contact ketoconazole shampoo-triggered pemphigus foliaceus in a dog.

Species:
dog
Skin & coatDogs

Plain-English summary

A 10-year-old spayed female cocker spaniel developed sudden skin problems, showing widespread pustules after using ketoconazole shampoo. Tests on her skin revealed that the pustules were caused by a condition called pemphigus foliaceus, which is an autoimmune skin disorder. This case highlights a possible reaction to the shampoo. If your dog shows similar skin lesions after using a new product, it's important to consult your veterinarian for proper diagnosis and treatment.

People also search for: dog skin problems after shampoo · cocker spaniel skin rash · pemphigus foliaceus treatment for dogs

Abstract

A 10-year-old spayed female cocker spaniel dog was referred for an evaluation of acute-onset generalized pustular cutaneous lesions following application of ketoconazole shampoo. Cytologic and histopathologic examinations of the lesions revealed intra-epidermal pustules with predominantly neutrophils and acantholytic cells. This is the first description of putative contact ketoconazole shampoo-triggered pemphigus foliaceus in a dog.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/28878412/