Pyrethroid toxicity in a Vietnamese pot-bellied pig.

Abstract

A 7-month-old spayed female Vietnamese pot-bellied pig (VPBP) was presented for diffuse muscle fasciculations and seizure-like activity that had started 4 hours before presentation. The pig was stuporous and displayed diffuse involuntary gross motor movement and muscle fasciculations, as well as hypertonicity of all 4 limbs. Hematologic analysis revealed hemoconcentration, severe hyperlactatemia, moderate metabolic acidosis, increased creatine kinase and gamma-glutamyltransferase. The pig failed to respond to diazepam, propofol, methocarbamol, and supportive care, followed by general anesthesia, and was euthanized. Bifenthrin, a pyrethroid insecticide, was identified by gas chromatography-mass spectrometry of stomach contents. Pyrethroid insecticide toxicity in VPBP may result in clinical signs similar to those seen in companion animals.