Peer-reviewed veterinary case report
Pregnant mare with nonhealing leg wound and bone lesions
By Worster, A A et al.·Published in Journal of the American Veterinary Medical Association·2000·Department of Clinical Sciences, United States·View original on PubMed →
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Original publication title: Pythiosis with bone lesions in a pregnant mare.
- Species:
- horse
Plain-English summary
A 9-year-old pregnant mare had a nonhealing wound on her left front leg that lasted for 8 weeks. After tests showed a serious infection caused by a fungus called Pythium, she was treated with antibiotics, special dressings, and surgery to remove the infected tissue and part of the bone. Despite the severity of her condition, the mare recovered well and later gave birth to a healthy foal. This case highlights the effectiveness of targeted antifungal treatment in managing serious infections in horses.
People also search for: pregnant mare wound treatment · Pythium infection in horses · mare bone infection recovery
Abstract
A 9-year-old pregnant mare was referred for evaluation of a nonhealing wound of 8 weeks' duration on the lateral aspect of the left forelimb. A soft tissue mass encircled the proximal two thirds of the metacarpus; radiography revealed a moderate periosteal reaction affecting metacarpal bone i.v. Histologic and immunohistochemical examinations revealed eosinophilic granulomatous inflammation and Pythium sp in the soft tissues. The mare was treated for 12 days with antimicrobials, medicated wound dressings, debridement, and i.v. administration of sodium iodide; radiography revealed progression of the bone lesions. The mare was treated by regional arterial perfusion with miconazole and excision of affected soft tissues and the distal two thirds of metacarpal bone i.v. The mare recovered without complications and gave birth to a healthy foal. Regional perfusion of antifungal agents provides high concentrations in soft and osseous tissues and permits use of low dosages of agents administered by other routes, which reduces cost, adverse effects, and teratogenic effects.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/10844973/