Peer-reviewed veterinary case report
Bone density loss in dogs with hyperadrenocorticism shown by CT scan
By Lee, Donghoon et al.·Published in Journal of veterinary science·2015·Department of Medical Imaging, South Korea·View original on PubMed →
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Original publication title: Quantitative CT assessment of bone mineral density in dogs with hyperadrenocorticism.
- Species:
- dog
Plain-English summary
A group of dogs with hyperadrenocorticism (HAC), a condition that can lead to weakened bones, was studied to see how their bone density compared to healthy dogs. The researchers used a special type of CT scan to measure bone mineral density in 8 dogs with HAC and found that their bone density was significantly lower than in 39 normal dogs. This suggests that dogs with HAC may be at risk for bone problems due to lower bone density. The study highlights the importance of monitoring bone health in dogs with this condition.
People also search for: dog hyperadrenocorticism symptoms · low bone density in dogs · pituitary-dependent hyperadrenocorticism treatment
Abstract
Canine hyperadrenocorticism (HAC) is one of the most common causes of general osteopenia. In this study, quantitative computed tomography (QCT) was used to compare the bone mineral densities (BMD) between 39 normal dogs and 8 dogs with HAC (6 pituitary-dependent hyperadrenocorticism [PDH]; pituitary dependent hyperadrenocorticism, 2 adrenal hyperadrenocorticism [ADH]; adrenal dependent hyperadrenocorticism) diagnosed through hormonal assay. A computed tomogaraphy scan of the 12th thoracic to 7th lumbar vertebra was performed and the region of interest was drawn in each trabecular and cortical bone. Mean Hounsfield unit values were converted to equivalent BMD with bone-density phantom by linear regression analysis. The converted mean trabecular BMDs were significantly lower than those of normal dogs. ADH dogs showed significantly lower BMDs at cortical bone than normal dogs. Mean trabecular BMDs of dogs with PDH using QCT were significantly lower than those of normal dogs, and both mean trabecular and cortical BMDs in dogs with ADH were significantly lower than those of normal dogs. Taken together, these findings indicate that QCT is useful to assess BMD in dogs with HAC.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/26040613/