Peer-reviewed veterinary case report
Echocardiographic ratios to assess mitral valve disease in dogs
By Brown, Donald J et al.·Published in Journal of veterinary internal medicine·2005·Department of Clinical Sciences, United States·View original on PubMed →
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Original publication title: Quantitative echocardiographic [corrected] evaluation of mitral endocardiosis in dogs using ratio indices.
- Species:
- dog
Plain-English summary
A group of dogs with heart problems, specifically mitral regurgitation due to chronic valvular disease, were evaluated using a special ultrasound technique called echocardiography. The researchers found that certain measurements could effectively identify dogs with these heart issues and help predict if they were also experiencing congestive heart failure. One specific measurement was particularly good at distinguishing between healthy dogs and those with heart disease. This information can help veterinarians better diagnose and manage heart conditions in dogs, leading to more effective treatments.
People also search for: dog heart problems symptoms · mitral regurgitation treatment in dogs · how to tell if my dog has congestive heart failure
Abstract
This study compares M-mode echocardiographic ratio indices (ERIs) in dogs with mitral regurgitation due to chronic valvular disease (CVD/MR) for their ability to discriminate and quantify associated echocardiographic changes. Weight-based M-mode ERIs were determined retrospectively for 2 groups of dogs, normal (n = 47) and CVD/MR (n = 176). The CVD/MR group was further subdivided into those with (CVD/MR B, n = 74) and without (CVD/MR A, n = 102) left-sided congestive heart failure (LCHF). ERIs were compared descriptively (summary statistics) and also by receiver-operator characteristic curve areas (ROCAs) for their ability to discriminate between groups. Univariate logistic regression (LR) models were used to estimate the odds ratio for each ERI as a predictor of the CVD/MR condition as well as to predict LCHF within the CVD/MR group. A novel ERI (wdeltaA), designed to express body size-normalized short-axis stroke area, was sensitive (90%) and specific (98%) to discriminate between normal and CVD/MR at a cutoff value of 1.8 standard deviations (wdeltaA = 2.1). Prediction of LCHF within the CVD/MR group was more problematic, but an ERI expressing left atrial size (wLA) showed 76% sensitivity and 81% specificity at a cutoff value of 5.2 standard deviations (wLA = 1.55). Ours was a descriptive study of echocardiographic patterns of pathology associated with CVD/ MR and determined which ERIs are sensitive and specific for CVD/MR and for LCHE ERIs normalize echocardiographic data for body size in dogs and are well-suited to quantitative descriptions and analysis.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/16095172/