Peer-reviewed veterinary case report
RAA-CRISPR-HCR cascade amplification for ultrasensitive visual detection of African swine fever virus DNA.
- Journal:
- Chemical communications (Cambridge, England)
- Year:
- 2026
- Authors:
- Wu, Hongyu et al.
- Affiliation:
- Institute of Advanced Materials (IAM) · China
Abstract
An RAA-CRISPR-HCR (RCH) cascade amplification system was developed, which generates an ultrasensitive colorimetric response to low concentrations of African swine fever virus (ASFV) DNA with a detection limit of 1 copy µL. It demonstrates excellent accuracy and specificity in real samples, facilitating efficient on-site visual early detection of ASFV.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/41645777/