Peer-reviewed veterinary case report
Radiation and cisplatin treatment for bladder cancer in dogs
By McCaw, Dudley L. & Lattimer, Jimmy C.·Published in Veterinary Radiology·1988·View original on Crossref →
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Original publication title: RADIATION AND CISPLATIN FOR TREATMENT OF CANINE URINARY BLADDER CARCINOMA
- Species:
- dog
Plain-English summary
Two dogs with urinary bladder cancer were treated with a combination of radiation and a chemotherapy drug called cisplatin. One dog received a total of 4400 cGy of radiation, while the other received 4800 cGy, along with cisplatin given before some of the radiation treatments. After the therapy, tests showed that the tumors in both dogs had shrunk, and they tolerated the treatment well with only minor side effects.
People also search for: dog bladder cancer treatment · cisplatin for dogs · radiation therapy for dog cancer
Abstract
Two cases of canine urinary bladder carcinoma were treated with combined radiation and cisplatin. Total radiation dose was 4400 cGy for one dog and 4800 cCy for the other. Cobalt 60 radiation was fractioned using 400 cGy per fraction. Cisplatin was administered intraarterially at a dose of 50 mg/m2 divided equally six to seven hours before the first three radiation fractions. Cisplatin was administered before the last three radiation fractions at the same dose and time, but was infused intravenously. Objective evaluation using double contrast cystograms revealed reduction in tumor size in both dogs. The therapy was well‐tolerated with minimal side effects.
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Search related cases →Original publication on Crossref: https://doi.org/10.1111/j.1740-8261.1988.tb01777.x