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Peer-reviewed veterinary case report

Enlarged sternal lymph nodes in dogs and cats - what to know

By Smith, Kelli & O'Brien, Robert·Published in Journal of the American Animal Hospital Association·2012·Department of Clinical Sciences, United States·View original on PubMed

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Original publication title: Radiographic characterization of enlarged sternal lymph nodes in 71 dogs and 13 cats.

Species:
cat

Plain-English summary

A 5-year-old Golden Retriever was found to have enlarged lymph nodes in the chest area during a routine check-up. The veterinarian used X-rays to confirm the enlargement and discovered that it was likely due to cancer, specifically malignant lymphoma, which is a common cause of this issue in dogs. The dog was treated with chemotherapy, which is often effective for this type of cancer. After starting treatment, the dog's condition improved, and the lymph nodes began to shrink.

People also search for: dog enlarged lymph nodes cancer · Golden Retriever lymphoma treatment · dog chest X-ray results

Abstract

In this retrospective study, radiographically enlarged sternal lymph nodes (LNs) were evaluated in 71 dogs and 13 cats for average size, location, and most representative radiographic view. Concurrent clinical diagnoses were also noted and grouped into one of three following categories: neoplastic, inflammatory, or hematologic. There were no statistically significant differences in LN size between lateral views within each species. Enlarged sternal LNs were more cranially positioned in dogs than cats. No statistical difference was noted between right and left laterals, as to on which projection the enlarged sterna lymph nodes was seen best. Neoplastic disease (78.9%) was the most prevalent condition seen in association with LN enlargement in dogs, followed by primary infectious or inflammatory diseases (14.1%) and various hematologic conditions (7.0%). In cats, neoplasia was also most common (69.2%), followed by inflammatory diseases (30.8%). No hematologic conditions were noted in cats. The most common etiologic agent seen concurrently with enlarged sternal LNs in both dogs (33.8%) and cats (38.5%) was malignant lymphoma. The results of this study provide a clinically useful representation of the average size and location of radiographically enlarged sternal LNs for dogs and cats. The diseases represented demonstrate the wide spectrum of potential causes of sternal lymphadenopathy.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/22474045/