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Peer-reviewed veterinary case report

Glucosamine and chondroitin help dogs with hip and elbow arthritis

By McCarthy, Grainne et al.·Published in Veterinary journal (London, England : 1997)·2007·Department of Small Animal Clinical Studies·View original on PubMed

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Original publication title: Randomised double-blind, positive-controlled trial to assess the efficacy of glucosamine/chondroitin sulfate for the treatment of dogs with osteoarthritis.

Species:
dog

Plain-English summary

A group of 35 dogs with osteoarthritis in their hips or elbows were treated with a combination of glucosamine and chondroitin sulfate (Glu/CS) to see if it could help reduce their pain and improve their ability to walk. The dogs were also given a common pain medication called carprofen for comparison. After about 10 weeks, the dogs receiving Glu/CS showed noticeable improvements in their pain and mobility, although it took longer for them to respond compared to those on carprofen. Overall, the study found that glucosamine and chondroitin can be effective for managing osteoarthritis in dogs.

People also search for: dog osteoarthritis treatment · glucosamine for dogs · carprofen vs glucosamine for arthritis

Abstract

Thirty-five dogs were included in a randomised, double-blind, positive controlled, multi-centre trial to assess the efficacy of an orally-administered glucosamine hydrochloride and chondroitin sulfate (Glu/CS) combination for the treatment of confirmed osteoarthritis of hips or elbows. Carprofen was used as a positive control. Dogs were re-examined on days 14, 42 and 70 after initiation of treatment. Medication was then withdrawn and dogs were re-assessed on day 98. Response to treatment was based on subjective evaluation by participating veterinarians who recorded their findings at each visit. Dogs treated with Glu/CS showed statistically significant improvements in scores for pain, weight-bearing and severity of the condition by day 70 (P<0.001). Onset of significant response was slower for Glu/CS than for carprofen-treated dogs. The results show that Glu/CS has a positive clinical effect in dogs with osteoarthritis.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/16647870/