Peer-reviewed veterinary case report
Cat with FIP eye inflammation treated successfully with oral drugs
By Addie, Diane D et al.·Published in Viruses·2020·Feline Infectious Peritonitis and Coronavirus Website, France·View original on PubMed →
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Original publication title: Rapid Resolution of Non-Effusive Feline Infectious Peritonitis Uveitis with an Oral Adenosine Nucleoside Analogue and Feline Interferon Omega.
- Species:
- cat
Plain-English summary
A 2-year-old male neutered Norwegian Forest Cat was brought in with eye problems, weight loss, and signs of infection due to non-effusive feline infectious peritonitis (FIP). The vet diagnosed the cat using a special test and started treatment with eye drops and an oral medication called Mutian. Within 50 days, the cat gained over a kilogram, his eye issues improved, and his overall health markers showed significant recovery. After stopping Mutian, the cat continued to improve with a low dose of another medication called feline interferon omega.
People also search for: cat eye problems treatment · FIP in cats · Norwegian Forest Cat weight loss · feline interferon omega for cats
Abstract
This is the first report of a successful treatment of a non-effusive feline infectious peritonitis (FIP) uveitis case using an oral adenosine nucleoside analogue drug and feline interferon omega, and alpha-1 acid glycoprotein (AGP) as an indicator of recovery. A 2-year-old male neutered Norwegian Forest Cat presented with uveitis, keratic precipitates, mesenteric lymphadenopathy and weight loss. The cat was hypergammaglobulinaemic and had a non-regenerative anaemia. Feline coronavirus (FCoV) RNA was detected in a mesenteric lymph node fine-needle aspirate by a reverse-transcriptase polymerase chain reaction-non-effusive FIP was diagnosed. Prednisolone acetate eye drops were administered three times daily for 2 weeks. Oral adenosine nucleoside analogue (Mutian) treatment started. Within 50 days of Mutian treatment, the cat had gained over one kilogram in weight, his globulin level reduced from 77 to 51 g/L and his haematocrit increased from 22 to 35%; his uveitis resolved and his sight improved. Serum AGP level reduced from 3100 to 400 μg/mL (within normal limits). Symmetric dimethylarginine (SDMA) was above normal at 28 μg/dL, reducing to 14 μg/dL on the cessation of treatment; whether the SDMA increase was due to FIP lesions in the kidney or Mutian is unknown. Mutian treatment stopped and low-dose oral recombinant feline interferon omega begun-the cat's recovery continued.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/33121021/