Rare infantile sepsis and meningitis caused by Pasteurella multocida: A case report

Abstract

This case report highlights a rare instance of Pasteurella multocida meningitis in a 2-month-old infant, complicated by subdural empyema. The pathogen was identified using next-generation sequencing (NGS), despite negative bacterial cultures, underscoring the diagnostic challenges. The strain was predicted to be resistant to meropenem and ampicillin, necessitating a tailored treatment approach. The strain was likely transmitted through a neighbor's dog, emphasizing the complexity of P. multocida transmission. This case underscores the importance of advanced diagnostic techniques and personalized therapy for managing rare, antibiotic-resistant infections.