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Peer-reviewed veterinary case report

Reactive mesothelial hyperplasia associated with chronic peritonitis in a 20-year-old Quarter horse.

Journal:
The Canadian veterinary journal = La revue veterinaire canadienne
Year:
2016
Authors:
Hoon-Hanks, Laura L et al.
Affiliation:
Department of Microbiology · United States
Species:
horse

Plain-English summary

A 20-year-old male Quarter horse was found to have peritonitis, which is inflammation of the abdominal lining, along with a condition called reactive mesothelial hyperplasia, where the cells in the lining grow more than usual. During surgery to investigate further, the veterinarians initially thought there might be a tumor, but further tests showed that wasn't the case. Thankfully, after treatment, the horse made a full recovery. This case highlights the challenges in telling apart reactive changes from cancerous ones in similar situations.

Abstract

A 20-year-old gelding was diagnosed with peritonitis and severe reactive mesothelial hyperplasia. Exploratory laparotomy findings were suggestive of a neoplastic etiology; however, additional diagnostics ruled this out and the horse made a full recovery. This report demonstrates the difficulty and value of differentiating between reactive and neoplastic mesothelial processes.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/27152035/