Peer-reviewed veterinary case report
Real-time PCR assay to detect the novel Clade Ib monkeypox virus, September 2023 to May 2024.
- Journal:
- Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
- Year:
- 2024
- Authors:
- Schuele, Leonard et al.
- Affiliation:
- Department of Viroscience · Netherlands
Abstract
Monkeypox virus (MPXV) is an emerging zoonotic pathogen with complex epidemiology necessitating rapid diagnosis and distinguishing between clades and subclades. The emerging Clade Ib lacks the genomic region used in the Clade I-specific assay from the Centers for Disease Control and Prevention. We report an MPXV real-time PCR to specifically detect Clade Ib. The assay demonstrated proficient sensitivity and specificity in 92 samples and can be included along other TaqMan-based assays to detect MPXV and distinguish between clades and subclades.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/39119722/