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Peer-reviewed veterinary case report

Recent advances in nano-molybdenum oxide for photothermal cancer therapy.

Year:
2025
Authors:
Chen S et al.
Affiliation:
College of Science · China

Abstract

Cancer remains a significant global health challenge, driving the search for innovative treatments. Photothermal therapy (PTT) has emerged as a promising approach, using photothermal agents to convert near-infrared (NIR) light into heat for tumor ablation. Among these agents, nano-molybdenum oxide, particularly non-stoichiometric MoO<sub>3-x</sub> (0 < x < 1), stands out due to its unique defect structure, strong NIR absorption, high photothermal conversion efficiency (PCE), and pH-responsive degradation. This review summarized recent advancements in nano-molybdenum oxide for PTT, covering its classification, synthesis, surface modification, and tumor-targeting mechanisms. Subsequently, we explored its applications in PTT and combination therapies, evaluated biocompatibility and toxicity, and discussed current achievements, challenges, and future perspectives in cancer treatment.

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Original publication: https://europepmc.org/article/MED/40063363