Peer-reviewed veterinary case report
Dipstick test detects leptospirosis antibodies in dogs
By Dey, S et al.·Published in The Veterinary record·2007·Indian Veterinary Research Institute, India·View original on PubMed →
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Original publication title: Recombinant antigen-based dipstick ELISA for the diagnosis of leptospirosis in dogs.
- Species:
- dog
Plain-English summary
A new test has been developed to help diagnose leptospirosis, a serious infection in dogs. This test uses a special dipstick that changes color when it detects antibodies in the dog's blood. It has shown to be very accurate, with a sensitivity of about 96% and specificity of nearly 94%, meaning it can reliably identify dogs that have been exposed to the bacteria. This could help veterinarians diagnose leptospirosis more quickly and accurately, leading to better treatment outcomes for affected dogs.
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Abstract
A recombinant LipL 32 antigen-based dipstick ELISA was developed as a screening test for the detection of leptospiral antibodies in serum samples from dogs. The antibodies were detected by a change in the colour of the substrate solution when the recombinant antigen-coated dipsticks were dipped into it. The relative sensitivity, specificity and accuracy of the test, compared with the standard microscopic agglutination test, were 95.9 per cent, 93.8 per cent and 94.8 per cent, respectively.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17293577/